Innovative Health Iniziativa Call 13: Approximately €85 million to address immune-related diseases in older adults, reduce animal testing, and promote early-stage healthcare innovation.

The Innovative Health Iniziativas has launched the thirteenth call, HORIZON-JU-IHI-2026-13-two-stage, which focuses on topics such as accelerating healthcare innovation through networks, the reducing the use of animals in drug safety studies , Decoding the immunological basis of aging- and immune-related diseases.

IHI is a partnership between the European Union and European industry associations representing the pharmaceutical, medical technology, biotechnology, digital health, and vaccines sectors. It aims to translate healthcare research and innovation into concrete benefits for patients and society, ensuring that Europe remains at the forefront of interdisciplinary, sustainable, and patient-centered healthcare research.

A budget of €84.8 million has been allocated for the thirteenth IHI call. This is a Research and Innovation Action.

The topics of the call are:

Topic 1: A network to power the next wave of European healthcare innovation – HORIZON-JU-IHI-2026-13-01, whose maximum financial contribution from IHI JU is €35 million. The indicative in-kind contribution from industrial partners is €10.7 million. The indicative in-kind contribution from IHI JU contributing partners is €4.3 million.
Topic 2: An AI-based toxicology model and framework to support exemptions from the requirement to include a second species in drug safety studies – HORIZON-JU-IHI-2026-13-02, whose maximum financial contribution from IHI JU is €9 million. The indicative in-kind contribution from industrial partners is €7.3 million. The indicative in-kind contribution from IHI JU contributing partners is €100.000.
Topic 3: Decoding the Immunoscience of Age-Related Immune-Mediated Diseases - HORIZON-JU-IHI-2026-13-03, for which the maximum financial contribution from IHI JU is €9.2 million. The indicative in-kind contribution from the industrial partners is €9.2 million.

Legal entities based in all Horizon Europe associated countries, including Canada, Switzerland, the United Kingdom, and South Korea, are eligible to participate in the call.

The thirteenth call has the following deadlines: the 8 October 2026 for the short proposal and the 21 April 2027 for the complete proposal.

For more information: info@iniziativa.cc

Latest Articles

Mission Innovation 2.0 – Clean Hydrogen: €82,6 million for research and innovation in the hydrogen supply chain

August 6, 2026

Green Tour: €109 million for energy efficiency and sustainability in tourism businesses

August 3, 2026

Battery Booster Facility: €1.5 billion in loans for battery cell production projects

August 3, 2026

Success Cases

EINSTAIN

Engine INSTallation And INtegration

Program: HORIZON - Clean Sky2
Project cost: €1.472.500,00
Contribution: €1.060.900,00
Date: January 2016

Management control

Design and support for the implementation of the management control system, the KPI dashboard for monitoring company performance and the optimization of organizational processes

Sector: Environmental analyses
Turnover: €4.090.257
Date: 2020

Tecno

Iniziativa Assisted Tecno in the M&A transaction for the acquisition of a 65% stake in Energika Srl; the transaction aims to consolidate the SustainTech practice.

Sector: Energy Services
Deal: M&A - buy side
Date: 2021
Value:ND

Empoli Football Club

Construction of the new Empoli FC stadium using the procedure established by Legislative Decree 38/2021

Date: 2024

ROMAN GROUP

Design and support for the implementation of the economic-financial control and management control system, the design of a KPI dashboard for monitoring company performance and the optimization of organizational processes

Sector: Call Center
Date: 2023

Business Process Reengineering

Business Process Reengineering intervention aimed at the upgrade and technological development of the company's IT assets; support in the design of the company performance monitoring system and in the optimization of organizational processes

Sector: Textile Company
Turnover: €36.081.512
Date: 2022

Scientific research

Establishment of the Italian Observatory on Public Participations in partnership with the University of Naples Federico II, the University of Rome Tor Vergata and the University of Milan Bicocca with the aim of carrying out studies, research, data analysis, and the development and publication of reports.

Sector: Public-owned companies - performance analysis
Date: 2020

Management control and company organization

Design and support for the implementation of the management control system, the KPI dashboard for monitoring company performance and the optimization of the organizational structure and organizational and compliance processes from an ESG perspective

Sector: Production of Plastic Materials
Date: 2023

NATURE 4.0

Acquisition of enabling technologies functional to the expansion of existing production capacity, for which it is also necessary to invest in masonry works and technological systems for the adaptation of work spaces.

Contract: Sustainable Investments 4.0
Project cost: €1.285.595,90
Non-refundable contribution: €642.797,95
Date: December 2022

Icimendue 2025

Improvement of product quality and consequent reduction of waste due to defects, thanks to the installation of automatic and innovative printing control systems.

Contract: Sustainable Investments 4.0
Project cost: €2.867.514,37
Non-refundable contribution: €1.433.757,10
Date: January 2023

Management control

Support for the implementation of industrial accounting and management control

Sector: Flexible Packaging Production
Date: 2026

Adequate Structures

Analysis and verification of the organizational, administrative, and accounting structures of Fabbrica Italiana dell'Innovazione

Sector: Certified Incubator
Date: 2026

Technical assistance

Technical assistance for programs and interventions co-financed with the ERDF ESF+ 2021-2027 Regional Program, with resources from the Development and Cohesion Fund (FSC 2021-2027).

Sector: Technical Assistance
Date: 2025

SEGLUCO

“Eating well and gluten-free: development of a gluten-free croissant (already cooked and frozen) with valuable nutritional characteristics

Contract: PON Horizon2020
Project cost: €2.336.625,00
Contribution to spending: €812.156,25
Concessionary Financing: €467.325,00
Date: June 2021

GEVEN SpA

Construction of a new production unit for the manufacture of aircraft seats

Contract: Law 181/89 and subsequent amendments.
Project cost: €10.441.948
Non-refundable contribution: €2.014.000
Concessionary Financing: €5.220.000
Date: October 2017

Evolutionary upgrading of the models in the assortment

Contract: Innovation Agreement
Project cost: €6.164.816,25
Contribution to spending: €2.073.702,19
Date: July 2022

PARTY

Fostering local energy investments in the Province of Matera

Program: Horizon
Project cost: €498.157,00
Contribution: €498.157,00
Date: October 2017

Medaarch

Iniziativa, as financial advisor, assisted Meedarch in the spin-off of the Mediterranea business unit and negotiated the entry of a new investor into the NewCo.

Sector: Architecture and design
Deal: M&A - sell side
Date: 2024
Value:ND

Teramo Local Health Authority

Technical assistance in the evaluation of a proposal relating to the concession for the drafting of the definitive and executive design, and for the construction of the new hospital facility and the management of some non-healthcare services.

Date: 2022

San Michele SRL Nursing Home

The company has acquired additional diagnostic equipment to expand the services offered.

Contract: ZES Credit - Article 16 of Legislative Decree 19.09.2023 n. 124
Project cost: €850.920,00
Contribution: €340.367,00

Municipality of Sondrio

Development of tender procedures and subsequent activities regarding the economic, financial and management aspects of an energy efficiency intervention for public lighting

Date: 2022

Heineken Italia SpA

Expansion of the production capacity of the Assemini site in order to cover the growing market demands for the products of the Ichnusa range

Contract: Development Contract
Project cost: €61.123.573,72
Non-refundable contribution: €13.890.446,72
Date: April 2022

CASTLE

CAbin Systems design Toward passenger well-being

Program: HORIZON - Clean Sky2
Project cost: €11.695.656,00
Contribution: €9.533.525,00
Date: July 2016

Business organization

Intervention to modernize and optimize the company's organizational and management structure, with consequent updating of the Organization Regulations and the Organization Implementation Regulations, aimed at making management more efficient

Sector: Computer programming activities
Turnover: €16.392.207
Date: 2022

Engineering SpA

Consultancy and support for economic-financial and procedural aspects in all phases of the procedure relating to a PPP initiative (pursuant to paragraph 15 art. 183 Legislative Decree 50/2016) relating to an intervention of "Implementation of the Physical and IT infrastructures for the management of the drug cycle, treatment aids and physical and information flows for the Ragusa ASP"

Sector: Hospital
Date: 2019

ISTHMUS

Smart Infrastructures for Transport and Mobility

Contract: Major R&D Projects
Project cost: €5.578.468,75
Contribution to spending: €1.834.279,63
Concessionary Financing: €1.115.693,75
Date: June 2021

City of Lucca

Supporting the RUP in evaluating and managing PPP proposals submitted by private operators, ensuring full regulatory compliance and transparency. The goal is to promote innovative solutions and improve the efficiency of public spending, including through training and ongoing support for internal staff.

Date: 2024-2025/XNUMX/XNUMX

Sustainability reports

Support in the preparation of the corporate sustainability report and definition of the ESG strategy and indicators for monitoring sustainable variables

Sector: Production of Plastic Materials
Date: 2023

Training

Design and delivery of training on corporate finance management: "Knowing the present to plan the future" to the top figures of 30 SMEs, in collaboration with the Naples Industrial Union

Sector: Banking
Date: 2022

Pisa Sporting Club

Iniziativa acted as financial advisor in structuring the financing transaction for the construction of the Pisa Training Centre.

Sector: Sports Facilities
Deal: Debt Arrangement
Date: 2026
Value: 3.000.000,00

€1.9 billion Production investments supported | €435 billion Investments in Research & Innovation subsidized | 200 active customers with hundreds of completed transactions | 100 Project Financing/PPP Operations Supported | €1.9 billion Production investments supported | €435 billion Investments in Research & Innovation subsidized | 200 active customers with hundreds of completed transactions | 100 Project Financing/PPP Operations Supported |